Description

n-[3-[5-Cyano-1-(4-Fluorophenyl)-3H-2-Benzofuran-1-Yl]Propyl]-2,2,2-Trifluoro-n-(Trideuteriomethyl)Acetamide is a high-purity, deuterated organic compound designed for advanced research and development. This specialized chemical is valued for its role as a key intermediate or reference standard in the synthesis of novel active pharmaceutical ingredients (APIs) and for use in metabolic and pharmacokinetic studies. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of fine chemicals focused on developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Deuterated Reference Standard: Used as an internal standard in quantitative analytical methods like LC-MS/MS for accurate drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolic Tracing: Employed in research to trace metabolic pathways and understand the biological fate of drug molecules due to its deuterium labeling.
• Preclinical Research: Serves as a key material in the discovery and preclinical development phases of new therapeutic agents.
• Fine Chemical Synthesis: Utilized in custom synthesis and the production of complex, high-value specialty chemicals for research purposes.

Basic Information

Product Name	n-[3-[5-Cyano-1-(4-Fluorophenyl)-3H-2-Benzofuran-1-Yl]Propyl]-2,2,2-Trifluoro-n-(Trideuteriomethyl)Acetamide
CAS No.	1189981-17-6
Molecular Formula	C21H16D3F4N2O2
Molecular Weight	404.38 g/mol
Synonyms	2,2,2-Trifluoro-N-(trideuteriomethyl)-N-[3-[5-cyano-1-(4-fluorophenyl)-3H-2-benzofuran-1-yl]propyl]acetamide; N-[3-[5-Cyano-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-1-yl]propyl]-2,2,2-trifluoro-N-(trideuteriomethyl)acetamide; Deuterated Trifluoroacetamide Derivative; 1189981-17-6; (CD3)CF3CON Derivative Benzofuran Intermediate
EINECS	Contact for details

Quality Control

Our n-[3-[5-Cyano-1-(4-Fluorophenyl)-3H-2-Benzofuran-1-Yl]Propyl]-2,2,2-Trifluoro-n-(Trideuteriomethyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and isotopic enrichment meet exacting specifications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Deuterium Incorporation (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.