Description

5-o-Desmethyl Omeprazole-D3 Sulfide CAS NO 1189968-01-1 is a deuterium-labeled analog of a key omeprazole metabolite, serving as a critical internal standard for precise quantitative analysis in bioanalytical studies. This high-purity reference material is essential for ensuring accuracy and reliability in pharmacokinetic and metabolic research, where measurement precision is paramount. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers engaged in drug metabolism and bioequivalence studies.

Application

• Primary use as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) for the quantification of omeprazole and its metabolites in biological matrices.
• Critical component in pharmacokinetic (PK) and bioequivalence (BE) studies to ensure data integrity and regulatory compliance.
• Supporting drug metabolism and disposition (DMPK) research for understanding the metabolic pathways of proton pump inhibitors.
• Utilized in the development and validation of highly sensitive and specific bioanalytical methods in clinical and preclinical settings.
• Reference material for quality control and assurance in laboratories performing therapeutic drug monitoring or metabolic profiling.

Basic Information

Item	Detail
Product Name	5-o-Desmethyl Omeprazole-D3 Sulfide
CAS No.	1189968-01-1
Molecular Formula	C16H16D3N3O2S
Molecular Weight	Approx. 314.41 g/mol
Synonyms	5-Hydroxy Omeprazole-D3 Sulfide; 5-O-Desmethyl Omeprazole Sulfide-d3; Omeprazole Metabolite Sulfide-d3; 5-OMZ-D3 Sulfide; 6-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl-d3)methyl]sulfinyl]-1H-benzimidazole; 6-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl-d3)methyl)sulfinyl)-1H-benzimidazole; 5-Hydroxy Omeprazole Sulfide Deuterated Standard
EINECS	Contact for details

Quality Control

Every batch of 5-o-Desmethyl Omeprazole-D3 Sulfide is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity suitable for sensitive analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) providing detailed results for identity, purity, and isotopic enrichment are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This compound is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98.0 atom % D
Chemical Purity (by HPLC)	≥ 95.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.