Description

3-Methylflavone-8-Carboxylic Acid-D5 is a high-purity, deuterium-labeled derivative of a key flavone carboxylic acid, serving as a critical stable isotope-labeled internal standard for advanced analytical applications. Its primary value lies in enabling precise quantification and method validation in complex matrices, ensuring data integrity and regulatory compliance in sensitive research and development. This compound is essential for scientists and quality control professionals in the pharmaceutical, agrochemical, and analytical chemistry industries, particularly for pharmacokinetic studies, metabolic profiling, and environmental fate analysis.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis in bioanalytical and pharmacokinetic studies.
• Quantitative reference material for the analysis of non-labeled 3-Methylflavone-8-Carboxylic Acid and related metabolites.
• Use in method development and validation for regulatory submissions to agencies like the FDA and EMA.
• Metabolic pathway tracing and drug metabolism studies in pharmaceutical R&D.
• High-purity reagent for synthesizing more complex deuterated compounds for research.
• Quality control and assurance in the production of active pharmaceutical ingredients (APIs).
• Environmental analysis for tracing the fate of chemical compounds.

Basic Information

Product Name	3-Methylflavone-8-Carboxylic Acid-D5
CAS No.	1189883-79-1
Molecular Formula	C17H7D5O4
Molecular Weight	~287.30 g/mol
Synonyms	8-Carboxy-3-methylflavone-d5; 3-Methyl-8-flavonecarboxylic Acid-d5; Deutero-3-Methylflavone-8-Carboxylic Acid; 3-Methyl-2-phenyl-4H-chromene-8-carboxylic-2,3,4,5,6-d5 Acid; 3-Methyl-2-phenyl-4H-1-benzopyran-8-carboxylic-2,3,4,5,6-d5 Acid; 3-Methylflavone-8-carboxylic Acid (phenyl-d5); [D5]-3-Methylflavone-8-carboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 3-Methylflavone-8-Carboxylic Acid-D5 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including HPLC for chemical purity and MS for isotopic enrichment. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformity to your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (MS)	≥98 atom % D
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.