Description

4-Hydroxy-3-[3-[(1-Methylethyl-D7)Amino]-1-Phenylpropyl]-Benzoic Acid is a deuterated isotopologue of a key pharmaceutical intermediate, offering enhanced metabolic stability for advanced research and development. This compound is critical for conducting mass spectrometry studies, pharmacokinetic (PK/ADME) profiling, and the synthesis of deuterated drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and contract research organizations (CROs) focused on innovating new therapeutic agents.

Application

• Deuterated Drug Synthesis: As a building block for creating novel active pharmaceutical ingredients (APIs) with improved metabolic profiles.
• Metabolic Stability Studies: Used as an internal standard or reference compound in mass spectrometry for accurate quantification and metabolite identification.
• Pharmacokinetic (PK) and ADME Research: Essential for tracing drug absorption, distribution, metabolism, and excretion in preclinical studies.
• Isotope Labeling: Employed in mechanistic studies and pathway elucidation within medicinal chemistry programs.
• Analytical Reference Standard: Serves as a high-purity certified standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	4-Hydroxy-3-[3-[(1-Methylethyl-D7)Amino]-1-Phenylpropyl]-Benzoic Acid
CAS No.	1189868-60-7
Molecular Formula	C19H16D7NO3
Molecular Weight	~314.45 g/mol
Synonyms	4-Hydroxy-3-[3-[(1-Methylethyl-D7)amino]-1-phenylpropyl]benzoic acid; Deuterated Isotopologue of 4-Hydroxy-3-[3-(isopropylamino)-1-phenylpropyl]benzoic acid; (R,S)-4-Hydroxy-3-[3-[(1-Methylethyl-D7)amino]-1-phenylpropyl]benzoic acid; Benzoic acid, 4-hydroxy-3-[3-[(1-methylethyl-D7)amino]-1-phenylpropyl]-; D7-Isopropylamino labeled benzoic acid derivative; Pharmaceutical Intermediate D7
EINECS	Contact for details

Quality Control

Our deuterated compounds are manufactured under strict quality systems to ensure isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR (¹H, ²H) and LC-MS to confirm deuteration level and chemical purity. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic enrichment, and impurity profile is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuteration Degree (MS/NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.