Description

Racdidemethyl Citalopram-D6 Hydrochloride CAS NO 1189865-88-0 is a deuterated isotopologue of a key pharmaceutical intermediate, offering a stable, non-radioactive label for advanced analytical and research applications. This high-purity compound is essential for ensuring the accuracy and reliability of pharmacokinetic, metabolic, and bioanalytical studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers engaged in method development and validation.

Application

• Internal Standard for LC-MS/MS Analysis: Serves as a critical internal standard for the precise quantification of citalopram and related metabolites in complex biological matrices.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used in mass spectrometry-based studies to track drug absorption, distribution, metabolism, and excretion (ADME).
• Bioanalytical Method Development: Enables the development and validation of highly specific and sensitive analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).
• Pharmaceutical Impurity Profiling: Aids in the identification and characterization of process-related impurities and degradants during drug substance development.
• Stable Isotope Labeling in Research: Provides a tool for mechanistic studies in medicinal chemistry and neuropharmacology research.
• Quality Control Reference Material: Acts as a certified reference material for in-house quality control testing of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Racdidemethyl Citalopram-D6 Hydrochloride
CAS No.	1189865-88-0
Molecular Formula	C20H15D6FN2O•HCl
Molecular Weight	366.88 g/mol (approx.)
Synonyms	1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile-D6 Hydrochloride; Citalopram Dimethyl-D6 Hydrochloride; Citalopram Related Compound D6 HCl; Citalopram-D6 (N,N-dimethyl-D6) Hydrochloride; 1,3-Dihydro-1-[3-[(methyl-D3)amino]propyl]-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile-D3 Hydrochloride
EINECS	Contact for details

Quality Control

Our Racdidemethyl Citalopram-D6 Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and mass spectrometry, to confirm identity, chemical purity, isotopic enrichment, and absence of impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and compliance with your research or quality control protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥98 atom % D
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.