Description

o-Desmethyl Pantoprazole o-Sulfatediscontinued is a key sulfated metabolite and a critical reference standard used in pharmaceutical research and development. This compound is essential for the accurate analysis, quantification, and metabolic profiling of Pantoprazole, a widely prescribed proton pump inhibitor. It serves as a vital tool for researchers and quality control laboratories in the pharmaceutical and analytical chemistry sectors. The material is supplied to support method validation, impurity characterization, and bioanalytical studies.

Application

• Pharmaceutical Reference Standard: Primary use as a certified standard for the identification and quantification of Pantoprazole metabolites in drug substance and product testing.
• Metabolite Profiling & Pharmacokinetics: Critical for in-vitro and in-vivo studies to understand the metabolic pathways, clearance, and exposure levels of Pantoprazole.
• Impurity Characterization: Used to identify, monitor, and control process-related impurities and degradation products in Pantoprazole API manufacturing.
• Bioanalytical Method Development: Serves as a calibration standard in LC-MS/MS and HPLC methods for accurate bioanalysis in clinical and non-clinical studies.
• Regulatory Compliance & Documentation: Supports regulatory filings (e.g., FDA, EMA) by providing definitive proof of structure and purity for metabolite identification.
• Academic & Contract Research: Utilized in universities and CROs for fundamental research on drug metabolism and analytical chemistry techniques.

Basic Information

Item	Detail
Product Name	o-Desmethyl Pantoprazole o-Sulfatediscontinued
CAS No.	1189856-53-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Pantoprazole Sulfate Metabolite; Pantoprazole o-Sulfate; 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole o-Sulfate; Desmethyl Pantoprazole Sulfate; Pantoprazole M9 Metabolite; Pantoprazole Hydroxy Sulfate
EINECS	Contact for details

Quality Control

Every batch of o-Desmethyl Pantoprazole o-Sulfatediscontinued is produced and analyzed under strict quality management protocols. The material is characterized using advanced analytical techniques including HPLC, LC-MS, and NMR to confirm identity and ensure high purity suitable for use as a reference standard. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profile is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.