Description

(3-Chloro-4-Fluoro-Phenyl)-Acetic Acid Methyl Ester is a high-purity fluorinated aromatic ester building block critical for advanced organic synthesis. This compound matters as a versatile intermediate, enabling the introduction of both chloro and fluoro substituents onto a phenylacetic acid scaffold, which is a key motif in pharmaceutical and agrochemical discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for creating novel active ingredients, as well as by agrochemical manufacturers for developing new crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the chloro-fluoro-phenyl moiety enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic compounds used in electronic display technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and ester hydrolysis/transformation reactions to create more complex molecular architectures.
• Chemical Research & Development: Essential for academic and industrial labs exploring new fluorinated compounds and their properties.

Basic Information

Product Name	(3-Chloro-4-Fluoro-Phenyl)-Acetic Acid Methyl Ester
CAS No.	1189770-43-1
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	Methyl (3-chloro-4-fluorophenyl)acetate; (3-Chloro-4-fluorophenyl)acetic acid methyl ester; 2-(3-Chloro-4-fluorophenyl)acetic acid methyl ester; Methyl 2-(3-chloro-4-fluorophenyl)acetate; 3-Chloro-4-fluoro benzeneacetic acid methyl ester; Methyl (3-chloro-4-fluorobenzene)acetate; 1189770-43-1; Methyl 3-chloro-4-fluorophenylacetate
EINECS	Contact for details

Quality Control

Our (3-Chloro-4-Fluoro-Phenyl)-Acetic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.