Description

4-(Methylamino)-1-(3-Pyridyl)-1-Butanol-D3 is a deuterated analog of a key intermediate in the synthesis of pharmaceutical compounds. This high-purity, isotopically labeled material is essential for creating internal standards used in quantitative mass spectrometry, ensuring accurate pharmacokinetic and metabolic studies. It is primarily required by research institutions, pharmaceutical developers, and contract research organizations (CROs) engaged in advanced drug discovery and development, particularly for compounds targeting neurological pathways.

Application

• Deuterated Internal Standard for LC-MS/MS: Critical for the precise quantification of parent drugs and metabolites in bioanalytical assays (plasma, serum, tissue).
• Pharmaceutical R&D: Used in the synthesis and metabolic pathway tracing of deuterated drug candidates to improve metabolic stability.
• Metabolite Identification & Profiling: Aids in distinguishing drug-derived metabolites from endogenous compounds in complex biological matrices.
• Clinical Trial Support: Enables reliable and compliant bioanalysis for Phase I-IV clinical studies under GLP guidelines.
• Forensic & Doping Control Analysis: Serves as a reference standard for the accurate detection of specific substances in forensic toxicology.
• Isotope Dilution Mass Spectrometry (IDMS): Provides the gold standard for achieving high accuracy and precision in quantitative analytical methods.

Basic Information

Product Name	4-(Methylamino)-1-(3-Pyridyl)-1-Butanol-D3
CAS No.	1189642-32-7
Molecular Formula	C10H13D3N2O
Molecular Weight	183.25 g/mol
Synonyms	1-(3-Pyridinyl)-4-(methylamino)-1-butanol-d3; 4-(Methylamino)-1-(pyridin-3-yl)butan-1-ol-d3; 1-(Pyridin-3-yl)-4-(methylamino)butan-1-ol-d3; Deuterated 4-(Methylamino)-1-(3-Pyridyl)-1-Butanol; 4-Methylamino-1-(3-pyridyl)-1-butanol-d3; 3-Pyridinebutanol, 4-(methylamino)-, deuterated; (RS)-4-(Methylamino)-1-(3-pyridyl)butan-1-ol-d3
EINECS	Contact for details

Quality Control

This deuterated compound is manufactured under strict quality control protocols to ensure isotopic purity and chemical integrity, essential for reliable analytical results. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and MS, to confirm deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical purity, and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment and allowed to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.