Description

Dihydro Fenofibrate-D6 is a stable isotope-labeled analog of the active metabolite of fenofibrate, a widely used lipid-regulating agent. This high-purity deuterated standard is essential for ensuring the accuracy and reliability of quantitative bioanalytical methods, such as LC-MS/MS, in pharmacokinetic and metabolic studies. It is a critical tool for pharmaceutical R&D laboratories, clinical research organizations, and regulatory bodies focused on cardiovascular drug development and therapeutic drug monitoring.

Application

• Primary use as an Internal Standard for the precise quantification of fenofibrate and its metabolites in biological matrices via mass spectrometry.
• Supporting Pharmacokinetic (PK) and Bioequivalence Studies for generic and novel fenofibrate formulations.
• Facilitating Drug Metabolism and Disposition (DMPK) research to elucidate metabolic pathways.
• Enabling high-accuracy analysis in Therapeutic Drug Monitoring (TDM) and clinical trials.
• Use in Method Development and Validation to meet FDA, EMA, and ICH regulatory guidelines.
• Application in Stable Isotope Dilution Assays to correct for analyte loss during sample preparation.

Basic Information

Item	Detail
Product Name	Dihydro Fenofibrate-D6
CAS No.	1189501-82-3
Molecular Formula	C20H15D6ClO4
Molecular Weight	378.86 g/mol (for unlabeled form, contact for exact D6 weight)
Synonyms	Fenofibric Acid-d6; 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic-3,3,3-d3 Acid-d3; Isopropyl-d7 Fenofibrate Metabolite-d6; Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 3,3,3-d3, 1-d3; Deuterated Fenofibric Acid; D6-Fenofibric Acid; Stable Isotope Labeled Fenofibric Acid
EINECS	Contact for details

Quality Control

Every batch of Dihydro Fenofibrate-D6 is manufactured and tested under strict quality systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR, HPLC, and MS. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic enrichment, and solvent content to ensure compliance with your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (Enrichment)	≥98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.