Description

Rac Diethylpropion-D10 Hydrochloride is a deuterated isotopologue of the pharmaceutical compound diethylpropion hydrochloride, specifically designed for use as an internal standard in analytical chemistry. This high-purity reference material is critical for ensuring the accuracy and reliability of quantitative analyses, particularly in pharmacokinetic and metabolic studies. It is an essential tool for pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory testing facilities that require precise and traceable measurements in method development and validation.

Application

• Internal Standard for LC-MS/MS Analysis: Primary use as a quantitative reference in liquid chromatography-tandem mass spectrometry for the analysis of diethylpropion and its metabolites.
• Pharmaceutical Research & Development: Enables accurate pharmacokinetic (PK) and bioavailability studies during drug development.
• Forensic Toxicology: Supports the precise identification and quantification of diethylpropion in biological matrices for legal and clinical purposes.
• Metabolite Profiling: Used in metabolic stability and metabolite identification studies to track the parent drug.
• Method Development and Validation: Critical for developing, optimizing, and validating robust analytical methods in compliance with ICH and FDA guidelines.
• Quality Control in Manufacturing: Serves as a reference standard for the quality control of active pharmaceutical ingredients (APIs) and finished drug products.

Basic Information

Product Name	Rac Diethylpropion-D10 Hydrochloride
CAS No.	1189500-62-6
Molecular Formula	C13D10H9NO • HCl
Molecular Weight	~267.8 g/mol
Synonyms	Diethylpropion-d10 Hydrochloride; Amfepramone-d10 Hydrochloride; (±)-2-(Diethylamino)propiophenone-d10 Hydrochloride; 1-Phenyl-2-(diethylamino)propan-1-one-d10 Hydrochloride; Tenuate-d10; Anorex-d10; NSC 52964-d10; Rac Amfepramone-D10 HCl
EINECS	Contact for details

Quality Control

Our Rac Diethylpropion-D10 Hydrochloride is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for analytical applications. Each batch is fully characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry, to confirm identity, isotopic enrichment (D10, typically >98 atom % D), and chemical purity (typically >98%). Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0% (D10)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.