Description

1-Methyl-3-(3'-Pyridylcarbonyl-1,2',3',4',5',6'-13C6)-Pyrrolidinone CAS NO 1189492-36-1 is a high-purity, stable isotope-labeled pyrrolidinone derivative, specifically enriched with carbon-13 at six positions on the pyridyl ring. This compound is critical for advanced analytical applications where precise molecular tracking and quantification are required. It is primarily utilized by research scientists and quality control professionals in the pharmaceutical, agrochemical, and metabolomics sectors for use as an internal standard in mass spectrometry and NMR spectroscopy.

Application

• Internal Standard for LC-MS/MS: Provides highly accurate quantification in pharmacokinetic and bioanalytical studies due to its isotopic purity, minimizing matrix effects.
• Metabolite Tracing in Research: Enables the detailed study of drug metabolism pathways and the fate of active pharmaceutical ingredients (APIs) in biological systems.
• Pharmaceutical Impurity Profiling: Used as a reference standard to identify and quantify process-related impurities and degradants in drug substances.
• Agrochemical Environmental Studies: Assists in tracing the environmental fate and degradation products of complex agrochemicals.
• NMR Spectroscopy: Serves as a valuable tool for structural elucidation and reaction mechanism studies in synthetic chemistry.
• Clinical Diagnostics Development: Supports the development and validation of high-sensitivity diagnostic assays for disease biomarkers.

Basic Information

Product Name	1-Methyl-3-(3'-Pyridylcarbonyl-1,2',3',4',5',6'-13C6)-Pyrrolidinone
CAS No.	1189492-36-1
Molecular Formula	C11H10N2O (13C6)
Molecular Weight	~204.17 (Exact mass varies with isotopic enrichment)
Synonyms	1-Methyl-3-(pyridine-3-carbonyl)pyrrolidin-2-one-1,2',3',4',5',6'-13C6; 13C6-Labeled 1-Methyl-3-(3-pyridinylcarbonyl)-2-pyrrolidinone; 1-Methyl-3-(3-pyridoyl)pyrrolidin-2-one-13C6; Isotopically Labeled Pyrrolidinone Derivative; Carbon-13 Enriched Pyrrolidinone; NMR/MS Internal Standard 1189492-36-1
EINECS	Contact for details

Quality Control

Every batch of 1-Methyl-3-(3'-Pyridylcarbonyl-1,2',3',4',5',6'-13C6)-Pyrrolidinone is manufactured and tested under strict quality management systems. We guarantee high isotopic and chemical purity, with comprehensive characterization using NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing isotopic enrichment, purity, and identity are provided with each shipment to ensure traceability and compliance with your research or quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 99 atom % 13C (at specified positions)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.