Description

1-(4'-Methoxy-3'-Sulfonamidophenyl)-1-Propanone-Methyl-D3 is a deuterium-labeled organic compound, specifically a propiophenone derivative, serving as a critical stable isotope-labeled internal standard. This compound matters for its essential role in ensuring the accuracy and reliability of quantitative analytical methods, particularly in regulated environments. It is primarily needed by pharmaceutical research and development laboratories, contract research organizations (CROs), and analytical testing facilities for use in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) applications.

Application

• Quantitative Bioanalysis: Used as a deuterated internal standard for the precise quantification of its non-labeled counterpart or related metabolites in biological matrices (plasma, serum, urine) via LC-MS/MS.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Drug Metabolism Studies: Facilitates the identification and quantification of drug metabolites, aiding in metabolic pathway elucidation.
• Method Development and Validation: Critical for developing robust, sensitive, and specific analytical methods that meet regulatory guidelines (e.g., FDA, EMA).
• Quality Control in Pharmaceutical Manufacturing: Supports impurity profiling and assay validation for active pharmaceutical ingredients (APIs) and finished drug products.
• Forensic and Doping Control Analysis: Provides high-confidence results in the detection and quantification of specific compounds in complex samples.

Basic Information

Item	Detail
Product Name	1-(4'-Methoxy-3'-Sulfonamidophenyl)-1-Propanone-Methyl-D3
CAS No.	1189482-14-1
Molecular Formula	C11H12D3NO4S
Molecular Weight	Contact for details
Synonyms	1-Propanone, 1-[4-methoxy-3-(sulfonylamino)phenyl]-, methyl-d3; Deuterated 1-(4-Methoxy-3-sulfonamidophenyl)propan-1-one; 1-(4-Methoxy-3-sulfamoylphenyl)propan-1-one-methyl-d3; 3'-Sulfamoyl-4'-methoxypropiophenone-methyl-d3; Propiophenone-d3 derivative; Sulfonamide-labeled propiophenone; Stable Isotope-Labeled Internal Standard (SIL-IS); [Methyl-d3]-Labeled Sulfonamidophenyl Propanone
EINECS	Contact for details

Quality Control

Our deuterated standards are produced under strict quality control protocols to ensure isotopic purity, chemical purity, and batch-to-batch consistency essential for analytical accuracy. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing specifications such as isotopic enrichment (e.g., D3 ≥ 99%), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We support compliance with GMP/GLP principles for research and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 99.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.