Description

Bezafibrate-D4 CAS NO 1189452-53-6 is a stable isotope-labeled analog of the lipid-regulating agent bezafibrate, where four hydrogen atoms are replaced by deuterium. This high-purity internal standard is critical for ensuring the accuracy and reliability of quantitative analytical methods, particularly in pharmacokinetic and metabolic studies. It is an essential tool for pharmaceutical research and development laboratories, contract research organizations (CROs), and analytical testing facilities focused on cardiovascular drug development and bioanalytical method validation.

Application

• Primary use as an internal standard for the precise quantification of bezafibrate in biological matrices (e.g., plasma, serum, urine) via LC-MS/MS and GC-MS.
• Essential for bioanalytical method development and validation in support of clinical trials and non-clinical pharmacokinetic studies.
• Used in drug metabolism and pharmacokinetics (DMPK) research to study the absorption, distribution, metabolism, and excretion (ADME) profile of bezafibrate.
• Critical component in stable isotope dilution assays (SIDA) to achieve high analytical precision and compensate for sample preparation losses.
• Supports pharmaceutical quality control laboratories in developing and verifying impurity profiling methods.
• Applied in environmental and forensic analysis for the trace detection of bezafibrate and related compounds.

Basic Information

Product Name	Bezafibrate-D4
CAS No.	1189452-53-6
Molecular Formula	C19H16D4ClNO4
Molecular Weight	365.84 g/mol (approx.)
Synonyms	Bezafibrate-d4; 2-[4-[2-[(4-Chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic-3,3,4,4-d4 acid; Deuterated Bezafibrate; Bezafibrate (phenyl-d4); Bezalip-D4; BM 15,075-d4; [2H4]-Bezafibrate
EINECS	Contact for details

Quality Control

Our Bezafibrate-D4 is manufactured under strict quality management systems to ensure the highest standards of isotopic purity and chemical integrity. Each batch is subjected to rigorous analytical testing, including NMR, HPLC, and mass spectrometry, to confirm isotopic enrichment (typically ≥98% D) and chemical purity (typically ≥95%). A comprehensive Certificate of Analysis (COA) detailing batch-specific results for identity, assay, and purity is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (Deuterium Content)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.