Description

1-(4-Chloromethyl-2-Thiazoyl)Guanidine-13C3 Hydrochloride Salt is a stable isotope-labeled compound, specifically a 13C3-labeled guanidine derivative, designed for advanced analytical and research applications. Its core value lies in serving as an essential internal standard for the precise quantification and metabolic pathway tracing of its non-labeled counterpart in complex biological matrices using mass spectrometry. This high-purity material is critical for researchers and quality control professionals in the pharmaceutical and agrochemical industries, where accurate measurement of drug candidates, metabolites, or active ingredients is paramount for development and regulatory compliance.

Application

• Internal Standard for LC-MS/MS: Primary application as a quantitative internal standard in Liquid Chromatography-Tandem Mass Spectrometry for pharmacokinetic, bioanalytical, and metabolomic studies.
• Metabolic Pathway Research: Tracing and elucidating the metabolic fate and biotransformation pathways of thiazole-based compounds in vivo.
• Pharmaceutical R&D: Supporting the development and validation of analytical methods for novel drug substances and their degradation products.
• Stable Isotope Labeling Studies: Used in mechanistic studies to differentiate between endogenous and exogenous compounds or to study reaction mechanisms.
• Quality Control & Reference Standard: Acting as a certified reference material for ensuring the accuracy and precision of analytical assays in quality control laboratories.

Basic Information

Product Name	1-(4-Chloromethyl-2-Thiazoyl)Guanidine-13C3 Hydrochloride Salt
CAS No.	1189443-23-9
Molecular Formula	C413C3H9ClN4OS • HCl
Molecular Weight	Contact for details
Synonyms	1-(4-(Chloromethyl)thiazol-2-yl)guanidine-13C3 hydrochloride; Guanidine-13C3, N-[4-(chloromethyl)-2-thiazolyl]-, monohydrochloride; 2-Guanidino-4-chloromethylthiazole-13C3 Hydrochloride; 13C3-Labeled CMG Hydrochloride; [13C3]-1-(4-Chloromethyl-2-thiazolyl)guanidine HCl; Stable Isotope Labeled Thiazole Guanidine Derivative
EINECS	Contact for details

Quality Control

Our 1-(4-Chloromethyl-2-Thiazoyl)Guanidine-13C3 Hydrochloride Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity, isotopic enrichment, and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity (atom % 13C), and analytical results is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % 13C)	≥ 99%
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.