Description

Torsemide-D7 is a deuterium-labeled analog of the loop diuretic Torsemide, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity stable isotope-labeled compound is essential for ensuring accuracy and reliability in mass spectrometry-based analyses, particularly in pharmacokinetic and metabolism studies. It is a critical tool for pharmaceutical research and development, clinical laboratories, and forensic toxicology requiring precise quantification of Torsemide.

Application

• Internal Standard for LC-MS/MS: Primary application as a quantitative internal standard in Liquid Chromatography-Tandem Mass Spectrometry for accurate Torsemide measurement in biological matrices.
• Pharmacokinetic Research: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) studies in preclinical and clinical research.
• Drug Metabolism Studies: Used in metabolite identification and profiling to understand the biotransformation pathways of Torsemide.
• Bioanalytical Method Development & Validation: Critical for developing and validating robust, regulatory-compliant analytical methods in pharmaceutical R&D.
• Clinical and Forensic Toxicology: Supports accurate quantification of Torsemide in patient samples or forensic investigations.
• Quality Control in Pharmaceutical Manufacturing: Can be utilized in impurity profiling and assay development for drug substance and product quality control.

Basic Information

Product Name	Torsemide-D7
CAS No.	1189375-06-1
Molecular Formula	C16H13D7N4O3S
Molecular Weight	349.43 g/mol
Synonyms	1-Isopropyl-3-[(4-m-toluidino-3-pyridyl)sulfonyl]urea-d7; Torasemide-D7; 4-[(5-Methyl-1H-imidazol-4-yl)methylamino]pyridine-3-sulfonamide-d7 (deuterated form); Demadex-D7; Unat-D7; Stable Isotope Labeled Torsemide; Torsemide (phenyl-d7); [D7]-Torsemide
EINECS	Contact for details

Quality Control

Our Torsemide-D7 is manufactured under strict quality control protocols to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and LC-MS. A comprehensive Certificate of Analysis (COA) is provided, detailing isotopic enrichment (typically ≥98% D), chemical purity (≥95% by HPLC), and analytical data. We support compliance with GMP/GLP standards for research and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (by NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.