Description

10α-Hydroxy-β-Morphine is a specialized morphine derivative and a key intermediate in advanced pharmaceutical research and synthesis. This compound is of significant interest for its role in the development and study of opioid receptor ligands and novel analgesic pathways. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of central nervous system (CNS) active substances and reference standards.

Application

• Pharmaceutical Reference Standard: Serves as a critical analytical standard for quality control and method development in opioid pharmaceutical manufacturing.
• Medicinal Chemistry Research: Used as a key synthetic intermediate or precursor in the research and development of new opioid analgesics and receptor modulators.
• Metabolite Studies: Employed in pharmacological and toxicological studies to investigate the metabolism and biotransformation pathways of morphine and related alkaloids.
• Biochemical Research: Utilized in vitro and in vivo studies to explore the structure-activity relationships (SAR) of compounds interacting with opioid receptors.
• Fine Chemical Synthesis: Acts as a building block for the synthesis of more complex, high-value specialty chemicals and labeled compounds for research.

Basic Information

Product Name	10α-Hydroxy-β-Morphine
CAS No.	1188377-79-8
Molecular Formula	C₁₇H₁₉NO₄
Molecular Weight	301.34 g/mol
Synonyms	10α-Hydroxy-β-morphine; 10α-Hydroxy-β-morphinan-3,6-diol; 10α-Hydroxy-7,8-didehydro-4,5α-epoxy-17-methylmorphinan-3,6α-diol; 10α-Hydroxyisomorphine; 10α-OH-β-Morphine
EINECS	Contact for details

Quality Control

Every batch of 10α-Hydroxy-β-Morphine is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with each shipment to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.