Description

2-(tert-Butyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is a high-value, functionalized phenolic boronic ester building block, essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in pharmaceutical and advanced material development. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring phenolic or sterically hindered biaryl structures.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators that incorporate phenolic motifs.
• Material Science & Organic Electronics: Serves as a monomer or precursor for conjugated polymers, OLED (Organic Light-Emitting Diode) materials, and other advanced organic semiconductors.
• Ligand & Catalyst Development: Utilized to create novel bidentate or monodentate ligands for transition metal catalysis, enhancing reaction selectivity and efficiency.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and sensors due to its boronate ester functionality.
• Academic & Contract Research: A vital reagent for methodological development in organic synthesis and exploratory research within university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	2-(tert-Butyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No.	1188335-77-4
Molecular Formula	C16H25BO3
Molecular Weight	276.18 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-tert-butylphenol; 2-tert-Butyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; 2-(tert-Butyl)-4-(pinacolatoboryl)phenol; 4-Pinacolatoboryl-2-tert-butylphenol; Phenol, 2-(1,1-dimethylethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-tert-Butyl-4-boronic acid pinacol ester phenol; 4-BPin-2-tert-butylphenol (abbrev.)
EINECS	Contact for details

Quality Control

Our 2-(tert-Butyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.