Description

n-(4-Hydroxyphenyl)-5-Methyl-2-1H-Pyridone-D4 is a deuterated isotopologue of a hydroxyphenyl pyridone derivative, a compound of significant interest in advanced research and development. This material is crucial for applications requiring precise molecular tracking and metabolic pathway elucidation, offering enhanced stability and analytical sensitivity. It is primarily utilized by pharmaceutical researchers, analytical chemists, and material scientists working in drug discovery, metabolism studies, and the development of specialized organic materials.

Application

• Pharmaceutical Research & Drug Discovery: Serves as a stable isotope-labeled internal standard for the quantitative bioanalysis of its non-deuterated counterpart in pharmacokinetic and metabolism studies.
• Metabolite Identification: Used in mass spectrometry to trace and identify drug metabolites, aiding in the understanding of biotransformation pathways.
• Mechanistic Studies: Facilitates research into reaction mechanisms and degradation pathways due to the kinetic isotope effect of the deuterium atoms.
• Analytical Method Development: Essential for developing and validating highly sensitive and specific LC-MS/MS methods in clinical and forensic toxicology.
• Organic Synthesis Intermediate: Acts as a specialized building block for synthesizing novel deuterated compounds for research purposes.
• Material Science Research: Investigated for potential use in the development of organic electronic materials or advanced polymers where isotopic purity can influence properties.

Basic Information

Item	Detail
Product Name	n-(4-Hydroxyphenyl)-5-Methyl-2-1H-Pyridone-D4
CAS No.	1188263-50-4
Molecular Formula	C12H7D4NO2
Molecular Weight	~201.23 g/mol
Synonyms	5-Methyl-2-(4-hydroxyphenyl)-1H-pyridin-4-one-d4; 5-Methyl-2-(4-hydroxyphenyl)-4-pyridone-d4; 2-(4-Hydroxyphenyl)-5-methyl-4(1H)-pyridinone-d4; Deuterated Hydroxyphenyl Methylpyridone; [D4]-n-(4-Hydroxyphenyl)-5-Methyl-2-1H-Pyridone; Stable Isotope Labeled Pyridone Derivative
EINECS	Contact for details

Quality Control

Every batch of n-(4-Hydroxyphenyl)-5-Methyl-2-1H-Pyridone-D4 is produced and analyzed under strict quality protocols to ensure high isotopic and chemical purity, critical for research integrity. Our quality assurance includes comprehensive characterization by NMR (1H, 13C), mass spectrometry, and HPLC to confirm identity, deuterium incorporation, and purity. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment to support your compliance and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled under appropriate laboratory conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.