Description

5-(2-Carboxyethyl)-2-Hydroxyphenyl β-D-Glucopyranosiduronic Acid is a specialized glucuronide conjugate, a key intermediate in the synthesis and study of bioactive phenolic metabolites. This compound is of significant value for research and development in pharmaceutical and nutraceutical chemistry, where precise metabolic profiling is required. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors for developing analytical standards, reference materials, and novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for the quantification and identification of drug metabolites in pharmacokinetic and bioanalytical studies.
• Metabolite Synthesis: Serves as a critical intermediate in the chemical synthesis of complex glucuronidated metabolites for biological activity testing.
• Biochemical Research: Employed in enzymatic and in vitro studies to investigate Phase II metabolism pathways, specifically glucuronidation.
• Diagnostic Development: Utilized in the development of diagnostic assays and kits for detecting specific metabolic biomarkers in clinical samples.
• Nutraceutical Analysis: Applied in research to understand the bioavailability and metabolism of polyphenols and other plant-derived bioactive compounds.

Basic Information

Product Name	5-(2-Carboxyethyl)-2-Hydroxyphenyl β-D-Glucopyranosiduronic Acid
CAS No.	1187945-71-6
Molecular Formula	C15H18O10
Molecular Weight	358.30 g/mol
Synonyms	2-Hydroxy-5-(2-carboxyethyl)phenyl β-D-glucopyranosiduronic acid; (2R,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-[5-(3-hydroxy-3-oxopropyl)-2-hydroxyphenoxy]oxane-2-carboxylic acid; Glucuronide conjugate of 3-(2,5-Dihydroxyphenyl)propanoic acid; HPE-Glucuronide; DHPPA-Glucuronide; Phenolic acid glucuronide; β-Glucuronide intermediate
EINECS	Contact for details

Quality Control

Our production of 5-(2-Carboxyethyl)-2-Hydroxyphenyl β-D-Glucopyranosiduronic Acid adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay purity (by HPLC), identity confirmation (by IR and/or NMR), and impurity profiles are available upon request. We support compliance with relevant guidelines for analytical reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.