Description

1-Boc-6-Amino-4,4-Dimethyl-3,4-Dihydro-2H-Quinoline is a high-purity, protected amine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in quinoline-based therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and combinatorial chemistry libraries.
• Peptidomimetics & PROTACs: Serves as a versatile scaffold for designing peptide mimics and proteolysis-targeting chimeras (PROTACs).
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents and pesticides.
• Material Science Precursor: Building block for functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Used to create labeled compounds and probes for studying biological pathways.

Basic Information

Product Name	1-Boc-6-Amino-4,4-Dimethyl-3,4-Dihydro-2H-Quinoline
CAS No.	1187933-54-5
Molecular Formula	C16H22N2O2
Molecular Weight	274.36 g/mol
Synonyms	tert-Butyl 6-amino-4,4-dimethyl-3,4-dihydro-2H-quinoline-1-carboxylate; 1-Boc-6-amino-4,4-dimethyl-1,2,3,4-tetrahydroquinoline; 6-Amino-4,4-dimethyl-1,2,3,4-tetrahydroquinoline-1-carboxylic acid tert-butyl ester; 1-N-Boc-6-amino-4,4-dimethyl-1,2,3,4-tetrahydroquinoline; Boc-ADTQ; 1-(tert-Butoxycarbonyl)-6-amino-4,4-dimethyl-1,2,3,4-tetrahydroquinoline
EINECS	Contact for details

Quality Control

Our 1-Boc-6-Amino-4,4-Dimethyl-3,4-Dihydro-2H-Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.