Description

4-Methylaminomethyl-Piperidine-1-Carboxylic Acid tert-Butyl Ester Hydrochloride is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, nitrogen-containing scaffold with orthogonal protecting groups, enabling precise molecular construction for complex targets. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides requiring specific piperidine-based architectures.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetic Research: Integral for creating peptide analogs and mimetics in medicinal chemistry programs.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: A valuable reagent for methodology development and exploring new synthetic pathways in university and institutional labs.

Basic Information

Product Name	4-Methylaminomethyl-Piperidine-1-Carboxylic Acid tert-Butyl Ester Hydrochloride
CAS No.	1187930-55-7
Molecular Formula	C13H27ClN2O2
Molecular Weight	278.82 g/mol
Synonyms	1-Boc-4-(Methylaminomethyl)piperidine Hydrochloride; tert-Butyl 4-[(Methylamino)methyl]piperidine-1-carboxylate Hydrochloride; 4-(Methylaminomethyl)piperidine-1-carboxylic acid tert-butyl ester hydrochloride; 1-N-Boc-4-(methylaminomethyl)piperidine HCl; 4-(N-Methylaminomethyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester hydrochloride; 1-Piperidinecarboxylic acid, 4-[(methylamino)methyl]-, 1,1-dimethylethyl ester, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 4-Methylaminomethyl-Piperidine-1-Carboxylic Acid tert-Butyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.