Description

Methyl-(3-Trifluoromethoxy-Benzyl)-Amine CAS NO 1187929-30-1 is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the benzylamine scaffold with the trifluoromethoxy substituent, which can dramatically influence the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Key intermediate in the synthesis of pharmaceutical candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Building block for advanced agrochemicals, such as herbicides and fungicides, where the trifluoromethoxy group enhances biological activity.
• Precursor in material science for developing specialty polymers and liquid crystals with tailored properties.
• Versatile reagent in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Used in the development of radiolabeled tracers and probes for positron emission tomography (PET) imaging.
• Starting material for the synthesis of more complex fluorinated fine chemicals and ligands for catalysis.

Basic Information

Product Name	Methyl-(3-Trifluoromethoxy-Benzyl)-Amine
CAS No.	1187929-30-1
Molecular Formula	C9H10F3NO
Molecular Weight	205.18 g/mol
Synonyms	N-Methyl-1-[3-(trifluoromethoxy)phenyl]methanamine; 1-[3-(Trifluoromethoxy)phenyl]-N-methylmethanamine; N-Methyl(3-trifluoromethoxybenzyl)amine; (3-Trifluoromethoxybenzyl)methylamine; α-Methylamino-3-trifluoromethoxytoluene; Benzenemethanamine, N-methyl-3-(trifluoromethoxy)-; Methyl-(3-trifluoromethoxy-benzyl)-amine
EINECS	Contact for details

Quality Control

Our Methyl-(3-Trifluoromethoxy-Benzyl)-Amine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting the exact specifications and test results. Our quality system is designed to meet the stringent requirements of research and cGMP-grade intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.