Description

4,4,4-Trifluoro-3-Trifluoromethyl-Butylamine Hydrochloride is a high-value fluorinated amine salt, a key building block in advanced organic synthesis. Its unique perfluoroalkyl-substituted structure makes it an essential intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of fluorinated drug candidates, particularly in CNS and oncology research.
• Agrochemical Synthesis: Used in creating advanced fluorinated pesticides and herbicides with enhanced efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or modifier in the production of specialty polymers with unique surface properties.
• Liquid Crystal & OLED Materials: Incorporated into fluorinated components for electronic display and lighting applications.
• PET Tracer Development: Utilized in radiochemistry for labeling compounds used in positron emission tomography.
• Chemical Biology Probes: Acts as a building block for creating fluorinated probes to study biological systems.

Basic Information

Product Name	4,4,4-Trifluoro-3-Trifluoromethyl-Butylamine Hydrochloride
CAS No.	1187928-35-3
Molecular Formula	C5H8ClF6N
Molecular Weight	231.57 g/mol
Synonyms	1,1,1-Trifluoro-2-(trifluoromethyl)butan-4-amine hydrochloride; 4,4,4-Trifluoro-3-(trifluoromethyl)butan-1-amine hydrochloride; 3-(Trifluoromethyl)-4,4,4-trifluorobutylamine hydrochloride; 4-Amino-1,1,1-trifluoro-2-(trifluoromethyl)butane hydrochloride; FC-113a Amine Hydrochloride (common trade name style); Perfluoroisobutylamine Hydrochloride (abbreviated); 4,4,4-Trifluoro-3-trifluoromethyl-butylamine HCl
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-3-Trifluoromethyl-Butylamine Hydrochloride is manufactured under strict quality management systems. We provide material with typical purities ≥98% (by HPLC/NMR), tailored to meet the stringent requirements of process development and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each batch to ensure traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.