Description

5-Fluoro-2,3-Dihydro-Benzofuran-3-Ylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key synthetic building block in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the benzofuran scaffold.
• Chemical Synthesis: Serves as a versatile chiral amine building block for constructing more complex heterocyclic compounds in medicinal chemistry.
• Life Science Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and biological pathways.
• Process Chemistry: Utilized for route scouting and optimization in the pilot-scale and commercial manufacturing of specialty chemicals.

Basic Information

Product Name	5-Fluoro-2,3-Dihydro-Benzofuran-3-Ylamine Hydrochloride
CAS No.	1187927-83-8
Molecular Formula	C8H9ClFNO
Molecular Weight	189.61 g/mol
Synonyms	5-Fluoro-2,3-dihydro-3-benzofuranamine hydrochloride; 3-Amino-5-fluoro-2,3-dihydrobenzofuran hydrochloride; 5-Fluoro-2,3-dihydrobenzofuran-3-amine HCl; 5-Fluoro-3-amino-2,3-dihydrobenzofuran hydrochloride; 1187927-83-8; 5-Fluoro-2,3-dihydro-1-benzofuran-3-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2,3-Dihydro-Benzofuran-3-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Ensure the storage area is well-ventilated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.