Description

(S)-1-Benzyl-1-(Boc-Amino)-3-Pyridin-4-Yl-Propan-2-One is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering precise stereochemical control essential for developing active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in areas requiring sophisticated organic synthesis. CAS number 1187926-99-3.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and antiviral targets.
• Peptidomimetic Synthesis: Used in constructing peptide-like molecules where the Boc-protected amino group and pyridine moiety are integral to bioactivity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in studies of enantioselective chemical transformations.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic properties of lead compounds.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Academic Research: Used in university and institutional labs for advanced organic chemistry methodology development and total synthesis projects.

Basic Information

Product Name	(S)-1-Benzyl-1-(Boc-Amino)-3-Pyridin-4-Yl-Propan-2-One
CAS No.	1187926-99-3
Molecular Formula	C20H24N2O3
Molecular Weight	340.42 g/mol
Synonyms	(S)-1-Benzyl-1-((tert-Butoxycarbonyl)amino)-3-(pyridin-4-yl)propan-2-one; (S)-1-Benzyl-1-(Boc-amino)-3-(4-pyridyl)-2-propanone; tert-Butyl (S)-(1-benzyl-2-oxo-3-(pyridin-4-yl)propyl)carbamate; (S)-N-Boc-1-Benzyl-3-(4-pyridyl)-2-propanoneamine; Boc-(S)-Amino Ketone Pyridine Derivative; (S)-1-Benzyl-1-(Boc-NH)-3-(4-Pyridyl)propan-2-one; 1187926-99-3
EINECS	Contact for details

Quality Control

Our (S)-1-Benzyl-1-(Boc-Amino)-3-Pyridin-4-Yl-Propan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.