Description

Lysine, N6-[(1,1-Dimethylethoxy)Carbonyl]- is a protected derivative of the essential amino acid L-lysine, where the N6-amino group is shielded by a tert-butoxycarbonyl (Boc) protecting group. This modification is critical for enabling selective peptide synthesis and chemical transformations in complex organic and biochemical research. It serves as a key building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity intermediates for the development of peptides, protein conjugates, and other bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Boc-protected amino acid for the sequential construction of peptides, ensuring regioselectivity during coupling reactions.
• Pharmaceutical Intermediate: Used in the research and development of novel therapeutic peptides, hormones, and enzyme inhibitors.
• Bioconjugation: Serves as a precursor for creating site-specific modifications on proteins and antibodies for drug delivery and diagnostic applications.
• Chemical Biology Research: Employed in the study of protein structure-function relationships and the synthesis of labeled amino acids for metabolic studies.
• Protecting Group Strategy: The Boc group is acid-labile, making this compound essential for multi-step syntheses where orthogonal deprotection is required.

Basic Information

Item	Detail
Product Name	Lysine, N6-[(1,1-Dimethylethoxy)Carbonyl]-
CAS No.	1187656-20-7
Molecular Formula	C11H22N2O4
Molecular Weight	246.31 g/mol
Synonyms	N6-Boc-L-lysine; Boc-Lys-OH; (S)-2-Amino-6-((tert-butoxycarbonyl)amino)hexanoic acid; N-α-Boc-N-ε-Boc-L-lysine (common misnomer, verify structure); Nε-Boc-L-lysine; Boc-Lys; tert-Butyl N6-[(1,1-dimethylethoxy)carbonyl]-L-lysinate (related ester); L-Lysine, N6-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our N6-Boc-L-lysine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for research and pharmaceutical applications. A Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as assay, enantiomeric purity, and impurity profiles. We support compliance with relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	+20.0° to +23.0° (c=1 in 1N HCl)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.