Description

2-(2,6-Difluorobenzoyl)-6-Methylpyridine is a high-purity, advanced pharmaceutical intermediate characterized by its specific difluorobenzoyl and methylpyridine structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modifications. Pharmaceutical R&D teams and fine chemical manufacturers need it to develop next-generation drug candidates, leveraging its unique chemical scaffold to impart desired biological activity and pharmacokinetic properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the difluoro and pyridine motifs can enhance biological efficacy.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	2-(2,6-Difluorobenzoyl)-6-Methylpyridine
CAS No.	1187170-58-6
Molecular Formula	C13H9F2NO
Molecular Weight	233.21 g/mol
Synonyms	6-Methyl-2-(2,6-difluorobenzoyl)pyridine; 2,6-Difluoro-α-(6-methyl-2-pyridinyl)benzyl alcohol ketone; (2,6-Difluorophenyl)(6-methylpyridin-2-yl)methanone; 2-(2,6-Difluorobenzoyl)-6-picoline; 2-Pyridinecarboxylic acid, 6-methyl-, 2,6-difluorophenyl ketone
EINECS	Contact for details

Quality Control

Our 2-(2,6-Difluorobenzoyl)-6-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.