Description

Ethyl 2-(2,6-Difluorophenyl)Thiazole-4-Carboxylate is a high-purity, synthetically valuable heterocyclic building block. This compound is a critical intermediate in the development of advanced active pharmaceutical ingredients (APIs) and agrochemicals, where its unique difluorophenyl-thiazole core imparts desirable biological and physicochemical properties. It is primarily utilized by research and development teams, as well as production chemists, in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated heterocycles for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a building block for developing next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Chemical Research & Development: Used in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Material Science Precursor: Potential intermediate for the synthesis of specialty polymers, liquid crystals, or organic electronic materials due to its rigid, aromatic structure.
• Contract Manufacturing & Custom Synthesis: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and commercial production under cGMP guidelines.

Basic Information

Item	Details
Product Name	Ethyl 2-(2,6-Difluorophenyl)Thiazole-4-Carboxylate
CAS No.	1187056-38-7
Molecular Formula	C12H9F2NO2S
Molecular Weight	269.27 g/mol
Synonyms	Ethyl 2-(2,6-difluorophenyl)-1,3-thiazole-4-carboxylate; 4-Carbethoxy-2-(2,6-difluorophenyl)thiazole; 2-(2,6-Difluorophenyl)-4-thiazolecarboxylic acid ethyl ester; Ethyl 2-(2,6-difluorophenyl)-4-thiazolecarboxylate; 1187056-38-7; Ethyl 2-(2,6-difluorophenyl)thiazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(2,6-Difluorophenyl)Thiazole-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed and consider storage under an inert atmosphere for long-term preservation to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.