Description

4-Fluorobenzenesulphonic Acid Monohydrate is a versatile organosulfur compound that serves as a key fluorinated building block in advanced chemical synthesis. Its value lies in the combination of the strongly electron-withdrawing sulfonic acid group and the fluorine substituent, which allows for precise tuning of acidity and reactivity in complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based drugs and fluorinated compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Catalyst and Ligand Preparation: Serves as a precursor for creating specialized acid catalysts and fluorinated ligands used in homogeneous and heterogeneous catalysis.
• Polymer and Material Science: Incorporated into monomers for the production of ion-exchange resins, proton-conducting membranes (e.g., for fuel cells), and other high-performance polymers.
• Organic Synthesis Reagent: Functions as a strong acid catalyst or a protecting group agent in various organic transformations, including Friedel-Crafts alkylation and acylation reactions.
• Dye and Pigment Manufacturing: Employed in the synthesis of fluorinated dyes and pigments, where it modifies solubility and color fastness properties.

Basic Information

Product Name	4-Fluorobenzenesulphonic Acid Monohydrate
CAS No.	1186663-24-0
Molecular Formula	C6H5FO3S · H2O
Molecular Weight	192.17 g/mol (Anhydrous basis: 174.16 g/mol)
Synonyms	p-Fluorobenzenesulfonic Acid Monohydrate; 4-Fluorobenzenesulfonic Acid Hydrate; Benzenesulfonic Acid, 4-fluoro-, monohydrate; 4-Fluoro-1-sulfobenzene Monohydrate; p-Fluorophenylsulfonic Acid Monohydrate; 4-FBSA Monohydrate; FBSA Hydrate; 1-Fluoro-4-sulfobenzoic Acid Monohydrate (common misnomer)
EINECS	Contact for details

Quality Control

Our 4-Fluorobenzenesulphonic Acid Monohydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, Karl Fischer titration for water content, and spectroscopic identification, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed and under anhydrous conditions. Keep away from strong bases, oxidizing agents, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	8.0 - 10.0% (Theoretical for monohydrate: ~9.4%)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.