Description

2-Chloro-n-[(9H-Fluoren-9-Ylamino)Carbonyl]-6-Fluorobenzamide is a specialized organic compound designed for advanced chemical synthesis and research. This high-purity intermediate is critical for the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on medicinal chemistry, process development, and the synthesis of fluorinated bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring a fluorenyl-protected amine and halogenated benzamide scaffold.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocycles and amide-containing molecules in academic and industrial R&D.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) considerations.
• Chemical Biology Probes: Can be utilized in the design and synthesis of molecular probes for studying biological targets and pathways.

Basic Information

Product Name	2-Chloro-n-[(9H-Fluoren-9-Ylamino)Carbonyl]-6-Fluorobenzamide
CAS No.	1186372-20-2
Molecular Formula	C21H14ClFN2O2
Molecular Weight	380.80 g/mol
Synonyms	2-Chloro-N-({[(9H-fluoren-9-yl)amino]carbonyl})-6-fluorobenzamide; 6-Fluoro-2-chloro-N-[(9H-fluoren-9-ylcarbamoyl)]benzamide; 2-Chloro-6-fluoro-N-[(9H-fluoren-9-ylcarbamoyl)]benzamide; Fmoc-protected chlorofluorobenzamide derivative; N-(9-Fluorenylmethoxycarbonyl)-2-chloro-6-fluorobenzamide (common naming convention); Benzamide, 2-chloro-N-[[(9H-fluoren-9-ylamino)carbonyl]]-6-fluoro-; 1186372-20-2
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-[(9H-Fluoren-9-Ylamino)Carbonyl]-6-Fluorobenzamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically assessed via HPLC, NMR, and mass spectrometry. We support development and commercial projects with material suitable for research use and can provide material meeting more stringent specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.