Description

2-Methyl-5-(Trifluoromethyl)Piperazine (Mixture Of Cis And Trans Isomers) is a versatile fluorinated piperazine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group, is engineered to impart desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials with tailored surface properties.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethyl)Piperazine (Mixture Of Cis And Trans Isomers)
CAS No.	1186195-52-7
Molecular Formula	C6H11F3N2
Molecular Weight	168.16 g/mol
Synonyms	2-Methyl-5-(trifluoromethyl)piperazine; 5-(Trifluoromethyl)-2-methylpiperazine; 2-Methyl-5-(trifluoromethyl)-1,4-diazacyclohexane; 2-Methyl-5-trifluoromethylpiperazine; 1,4-Diazacyclohexane, 2-methyl-5-(trifluoromethyl)-; 2-Methyl-5-(trifluoromethyl)piperazine (cis- and trans- mixture)
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethyl)Piperazine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere after opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomer Ratio (Cis/Trans)	Reported on COA
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.