Description

(3-Amino-Piperidin-1-Yl)-Thiophen-3-Yl-Methanone Hydrochloride is a high-purity (98+%) pharmaceutical intermediate with the molecular formula C10H15ClN2OS and a molecular weight of 246.76. This compound is a critical building block in modern medicinal chemistry, valued for its piperidine and thiophene moieties which are key scaffolds in drug discovery. It is primarily utilized by research institutions and pharmaceutical manufacturers developing novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting G-protein-coupled receptors (GPCRs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Used in the construction of complex molecules for potential therapeutics in neurology and psychiatry.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	(3-Amino-Piperidin-1-Yl)-Thiophen-3-Yl-Methanone Hydrochloride
CAS No.	1185316-70-4
Molecular Formula	C10H15ClN2OS
Molecular Weight	246.76 g/mol
Synonyms	1-(Thiophen-3-ylcarbonyl)-3-aminopiperidine hydrochloride; 3-Amino-1-(thiophene-3-carbonyl)piperidine hydrochloride; (3-Aminopiperidin-1-yl)(thiophen-3-yl)methanone hydrochloride; 3-APTH HCl; Thiophene-3-carboxylic acid (3-amino-1-piperidinyl) ester hydrochloride; 1-(3-Thienylcarbonyl)-3-aminopiperidine HCl
EINECS	Contact for details

Quality Control

Our (3-Amino-Piperidin-1-Yl)-Thiophen-3-Yl-Methanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure a purity of 98+% and confirm identity and consistency. Certificates of Analysis (COA) with full traceability are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.