Description

n-(Piperidin-4-Yl)Thiophene-3-Carboxamide Hydrochloride is a high-purity organic building block and pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the development of novel therapeutic agents, offering a key structural motif for drug discovery. It is primarily utilized by R&D laboratories, CROs, and pharmaceutical manufacturers focused on synthesizing new chemical entities for biological screening and lead optimization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead compound optimization.
• Biochemical Tool Compound: Used in the development of probes and inhibitors for studying specific biological pathways and enzyme functions.
• Contract Research & Development: Essential for CROs and CDMOs engaged in custom synthesis and process development for client projects.
• Academic Research: Employed in university and institutional labs for exploratory organic synthesis and pharmacological studies.
• Library Synthesis: A valuable building block for creating diverse compound libraries for high-throughput screening (HTS) campaigns.

Basic Information

Product Name	n-(Piperidin-4-Yl)Thiophene-3-Carboxamide Hydrochloride
CAS No.	1185314-33-3
Molecular Formula	C10H15N2OS • HCl
Molecular Weight	244.76 g/mol (Free base: 209.30 g/mol)
Synonyms	Thiophene-3-carboxamide, N-(4-piperidinyl)-, hydrochloride; 3-Thiophenecarboxamide, N-4-piperidinyl-, monohydrochloride; N-(Piperidin-4-yl)thiophene-3-carboxamide HCl; 4-(3-Thiophenecarboxamido)piperidine hydrochloride; 1185314-33-3; UNII-4V1V8C2Q8F; 4V1V8C2Q8F
EINECS	Contact for details

Quality Control

Our n-(Piperidin-4-Yl)Thiophene-3-Carboxamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.