Description

2-Chloro-n-(4-Piperidin-1-Ylmethyl-Phenyl)-Acetamide Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a CAS number of 1185296-68-7. This compound is critical for medicinal chemistry research and the development of novel therapeutic agents, particularly in central nervous system (CNS) and receptor-targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of proprietary drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel targets.
• API Development: Serves as a precursor in the development and scale-up of Active Pharmaceutical Ingredients (APIs).
• Contract Synthesis: Supplied to CROs and CDMOs for custom synthesis projects and process development.
• Biochemical Research: Employed as a tool compound in biochemical assays and pharmacological profiling.
• Library Synthesis: Used for generating focused chemical libraries for high-throughput screening (HTS).

Basic Information

Product Name	2-Chloro-n-(4-Piperidin-1-Ylmethyl-Phenyl)-Acetamide Hydrochloride
CAS No.	1185296-68-7
Molecular Formula	C15H22Cl2N2O
Molecular Weight	317.25 g/mol
Synonyms	2-Chloro-N-[4-(piperidin-1-ylmethyl)phenyl]acetamide hydrochloride; 2-Chloro-N-(4-((piperidin-1-yl)methyl)phenyl)acetamide HCl; 1185296-68-7; N-(4-(Piperidin-1-ylmethyl)phenyl)-2-chloroacetamide hydrochloride; 2-Chloroacetamide, N-[4-(1-piperidinylmethyl)phenyl]-, hydrochloride; UNII-9J2G8K8U4P; 9J2G8K8U4P
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-(4-Piperidin-1-Ylmethyl-Phenyl)-Acetamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.