Description

Terbinafine-D7 Hydrochloride is a deuterium-labeled analog of the antifungal agent terbinafine hydrochloride, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity compound is essential for ensuring accuracy and reliability in mass spectrometry-based analyses, particularly in pharmacokinetic and metabolic studies. It is a critical tool for pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory testing facilities focused on developing and validating robust bioanalytical assays for antifungal agents.

Application

• Primary use as an Internal Standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) for the quantification of terbinafine and its metabolites.
• Supporting Bioanalytical Method Development and Validation in preclinical and clinical studies.
• Enabling accurate Pharmacokinetic (PK) and Toxicokinetic (TK) Profiling of antifungal drugs.
• Application in Drug Metabolism and Disposition (DMPK) Studies to track drug distribution and clearance.
• Use in Forensic and Anti-Doping Analysis for the precise detection of terbinafine.
• Quality control and reference standard in Pharmaceutical Manufacturing for assay purity testing.

Basic Information

Product Name	Terbinafine-D7 Hydrochloride
CAS No.	1185240-27-0
Molecular Formula	C21H18D7ClN • HCl
Molecular Weight	391.40 g/mol (approx.)
Synonyms	(E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine-d7 Hydrochloride; (E)-N-(6,6-Dimethylhept-2-en-4-ynyl)-N-methyl-1-naphthylmethylamine-d7 Hydrochloride; Terbinafine-d7 HCl; Lamisil-d7 Hydrochloride; Deuterated Terbinafine Hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Terbinafine-D7 Hydrochloride is manufactured under strict quality management systems and undergoes comprehensive analytical characterization to ensure identity, purity, and isotopic enrichment. Our products are supported by a detailed Certificate of Analysis (COA) that includes data from NMR, HPLC, and mass spectrometry. We adhere to relevant standards for high-purity reference materials to guarantee reliable and reproducible performance in sensitive analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant use and storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0% (Chemical Purity)
Isotopic Purity (D-content)	≥98.0 atom % D
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.