Description

n-Boc Fluvoxamine-D3 is a deuterated, Boc-protected derivative of the selective serotonin reuptake inhibitor (SSRI) fluvoxamine. This compound is specifically designed as a high-purity internal standard for analytical quantification in pharmaceutical research and development. It is essential for scientists and quality control laboratories in the pharmaceutical, contract research organization (CRO), and academic sectors who require precise and reliable reference materials for mass spectrometry (MS) and liquid chromatography-mass spectrometry (LC-MS/MS) methods.

Application

• Internal Standard for Bioanalysis: Primary use as a stable isotope-labeled internal standard for the accurate quantification of fluvoxamine in biological matrices (plasma, serum, urine) during pharmacokinetic and toxicokinetic studies.
• Pharmaceutical R&D: Critical reference material in drug metabolism and pharmacokinetics (DMPK) research to study the absorption, distribution, metabolism, and excretion (ADME) profile of fluvoxamine.
• Method Development & Validation: Used to develop, validate, and ensure the reproducibility and reliability of LC-MS/MS analytical methods in compliance with Good Laboratory Practice (GLP) and ICH guidelines.
• Clinical Trial Support: Enables precise measurement of drug concentrations in patient samples during clinical trials for depression, obsessive-compulsive disorder (OCD), and other indications.
• Quality Control (QC) Testing: Serves as a certified reference standard for in-house QC testing of active pharmaceutical ingredients (APIs) and finished drug products to verify identity and potency.
• Forensic & Anti-Doping Analysis: Applied in specialized testing laboratories for the definitive identification and quantification of fluvoxamine in forensic toxicology and sports anti-doping programs.

Basic Information

Product Name	n-Boc Fluvoxamine-D3
CAS No.	1185235-90-8
Molecular Formula	C20H22D3F3N2O3
Molecular Weight	401.44 g/mol (approximate)
Synonyms	(5-Methoxy-4-(trifluoromethyl)valerophenone O-(2-Aminoethyl)oxime-d3, N-Boc Derivative; tert-Butyl (E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone O-[2-(Amino-d3)ethyl]oxime Carbamate; Fluvoxamine-d3 N-Boc; Fluvoxamine-d3 tert-Butyl Carbamate; Deuterated Boc-Fluvoxamine; [2H3]-n-Boc Fluvoxamine; Internal Standard Fluvoxamine-d3 Boc
EINECS	Contact for details

Quality Control

Every batch of n-Boc Fluvoxamine-D3 is manufactured and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) that detail purity, isotopic enrichment, and impurity profiles, ensuring traceability and compliance with research standards. Our products undergo rigorous quality testing to ensure consistency and reliability for critical analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive); desiccants are recommended for long-term storage. Keep container tightly sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.