Description

4-(6-Fluoropyridin-2-Yl)Piperidine-4-Carbonitrile Hcl is a high-purity, advanced pharmaceutical intermediate with the CAS number 1185145-94-1. This compound is a critical building block in modern medicinal chemistry, valued for its unique piperidine-pyridine hybrid structure that enables precise molecular modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. Our supply ensures consistent quality and reliable availability to support your complex synthesis workflows.

Application

This specialized intermediate serves as a key precursor in the development of new chemical entities. Its primary applications include:

• Pharmaceutical Research: A crucial scaffold for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Development: Used in creating novel active ingredients for crop protection products, leveraging its fluorinated heterocyclic structure.
• Chemical Biology: Employed as a molecular probe or building block in the study of enzyme inhibition and receptor-ligand interactions.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Custom Synthesis: Provided to contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring complex heterocyclic chemistry.

Basic Information

Item	Details
Product Name	4-(6-Fluoropyridin-2-Yl)Piperidine-4-Carbonitrile Hydrochloride
CAS No.	1185145-94-1
Molecular Formula	C11H11FN3·HCl
Molecular Weight	239.68 g/mol (Free base)
Synonyms	4-(6-Fluoropyridin-2-yl)piperidine-4-carbonitrile hydrochloride; 4-(6-Fluoro-2-pyridinyl)-4-piperidinecarbonitrile hydrochloride; 4-Cyano-4-(6-fluoropyridin-2-yl)piperidine hydrochloride; 2-(4-Cyano-4-piperidinyl)-6-fluoropyridine hydrochloride; 1185145-94-1; 4-(6-Fluoropyridin-2-yl)piperidine-4-carbonitrile HCl
EINECS	Contact for details

Quality Control

Every batch of 4-(6-Fluoropyridin-2-Yl)Piperidine-4-Carbonitrile Hcl is manufactured under a strict quality management system. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and cGMP environments where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC / MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.