Description

Carbidopa-D5 is a deuterated internal standard of the pharmaceutical compound Carbidopa, specifically designed for use in quantitative analytical methods. This high-purity, isotopically labeled compound is essential for ensuring accuracy and reliability in mass spectrometry-based analyses, such as LC-MS/MS. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and quality control departments for pharmacokinetic studies, bioanalytical method development, and impurity profiling.

Application

• Internal Standard for LC-MS/MS quantification of Carbidopa in biological matrices (plasma, serum, urine).
• Bioanalytical method development and validation in pharmaceutical research.
• Metabolite identification and pharmacokinetic (PK) studies.
• Stability testing and impurity profiling of drug substances and products.
• Use in clinical research for accurate therapeutic drug monitoring.
• Supporting regulatory submissions (e.g., FDA, EMA) requiring validated analytical methods.

Basic Information

Product Name	Carbidopa-D5
CAS No.	1185134-76-2
Molecular Formula	C10H9D5N2O4
Molecular Weight	227.25 g/mol
Synonyms	(-)-L-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic Acid-d5; (S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropionic Acid-d5; Lodosyn-d5; MK-486-d5; Levodopa-d5 Carbidopa; Isotopically Labeled Carbidopa; Carbidopa (phenyl-d5)
EINECS	Contact for details

Quality Control

Our Carbidopa-D5 is manufactured under strict quality control protocols to ensure the highest isotopic purity and chemical integrity. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing specifications for isotopic enrichment, chemical purity, and absence of impurities. We adhere to relevant standards for reference materials to support your critical analytical work.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Chemical Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.