Description

Nor-Acetildenafil-D8 is a deuterated analog of a key pharmaceutical intermediate, distinguished by its stable isotopic labeling. This compound is critical for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical research and drug development. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities for method development, pharmacokinetic studies, and quality control of related active pharmaceutical ingredients (APIs).

Application

• Primary use as a stable isotope-labeled internal standard for Liquid Chromatography-Mass Spectrometry (LC-MS/MS) analysis.
• Method development and validation for the quantification of related pharmaceutical compounds in biological matrices.
• Pharmacokinetic and metabolism studies to track drug absorption, distribution, and excretion.
• Quality control and impurity profiling in the manufacturing of active pharmaceutical ingredients (APIs).
• Reference material for forensic analysis and anti-doping testing in sports.
• Supporting research in drug discovery and development pipelines.

Basic Information

Product Name	Nor-Acetildenafil-D8
CAS No.	1185117-07-0
Molecular Formula	C23H22D8N6O4
Molecular Weight	438.55 g/mol (approx.)
Synonyms	Noracetildenafil-d8; 2-[2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4(3H)-one-d8; Deuterated Nor-Acetildenafil; Acetildenafil Impurity D8; Nor-Acetildenafil (D8 labeled); PDE-5 Inhibitor Metabolite D8 Standard
EINECS	Contact for details

Quality Control

Our Nor-Acetildenafil-D8 is manufactured under strict quality management systems to ensure exceptional isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and high-resolution mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation is provided to guarantee reliable performance as a critical reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.