Description

Gabapentin-D4 is a stable isotope-labeled analog of the pharmaceutical compound Gabapentin, where four hydrogen atoms are replaced by deuterium. This product is essential as an internal standard in quantitative analytical methods, ensuring the highest accuracy and reliability in mass spectrometry-based assays. It is primarily required by pharmaceutical research laboratories, contract research organizations (CROs), and quality control departments for method development, validation, and bioanalytical studies.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of Gabapentin in complex biological matrices such as plasma, serum, and urine.
• Pharmaceutical R&D: Used in pharmacokinetic and pharmacodynamic studies to track drug metabolism and absorption.
• Clinical Research: Supports the development and validation of robust analytical methods for clinical trial sample analysis.
• Forensic Toxicology: Enables accurate measurement of Gabapentin levels in forensic investigations.
• Method Development & Validation: Serves as a reference standard to establish specificity, accuracy, and precision of new analytical procedures.
• Quality Control & Assurance: Ensures batch-to-batch consistency and purity verification in pharmaceutical manufacturing.

Basic Information

Product Name	Gabapentin-D4
CAS No.	1185039-20-6
Molecular Formula	C9H13D4NO2
Molecular Weight	175.25 g/mol (approx.)
Synonyms	1-(Aminomethyl)cyclohexaneacetic-2,2,3,3-d4 acid; Gabapentin (phenyl-d4); Gabapentin-d4; [2H4]-Gabapentin; Deuterated Gabapentin; GP 47680-d4; Neurontin-d4 (trade name related); CI-945-d4
EINECS	Contact for details

Quality Control

Our Gabapentin-D4 is manufactured under strict quality systems to meet the exacting requirements of analytical reference standards. Each batch undergoes comprehensive testing, including NMR and Mass Spectrometry for structural confirmation and isotopic purity verification. We provide a comprehensive Certificate of Analysis (COA) detailing purity, chemical purity, and isotopic enrichment, ensuring full traceability and compliance with relevant guidelines for reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chemical Purity (HPLC)	≥ 99.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.