Description

5-Hydroxy-2-[1-Methyl-1-[[Benzylcarbamoyl]Amino]Ethyl]-6-Methoxypyrimidine-4-Carboxylic Acid Methyl Ester-D3 is a deuterated pyrimidine derivative, a high-value synthetic intermediate and reference standard. Its core value lies in its utility for advanced pharmaceutical research, particularly in the development of deuterated drug candidates where the incorporation of deuterium can improve metabolic stability and pharmacokinetic profiles. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, especially those focused on metabolic studies, drug discovery, and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of deuterated active pharmaceutical ingredients (APIs) for clinical research.
• Metabolic Tracer: Used in drug metabolism and pharmacokinetics (DMPK) studies to track and analyze metabolic pathways.
• Reference Standard: Serves as an analytical standard for quality control and method validation in pharmaceutical analysis (e.g., HPLC, LC-MS).
• Deuterated Drug Discovery: Key precursor in the research and development of deuterium-labeled compounds aimed at enhancing drug efficacy and safety profiles.
• Biochemical Research: Employed in academic and industrial laboratories for studying enzyme inhibition and receptor binding mechanisms.
• Isotope Labeling: Used in the preparation of isotopically labeled compounds for mass spectrometry and NMR spectroscopy applications.

Basic Information

Product Name	5-Hydroxy-2-[1-Methyl-1-[[Benzylcarbamoyl]Amino]Ethyl]-6-Methoxypyrimidine-4-Carboxylic Acid Methyl Ester-D3
CAS No.	1185032-53-4
Molecular Formula	C₁₈H₂₁D₃N₄O₅
Molecular Weight	Contact for details
Synonyms	Methyl 5-hydroxy-2-[1-methyl-1-[[(phenylmethyl)carbamoyl]amino]ethyl]-6-methoxy-4-pyrimidinecarboxylate-d3; Deuterated Pyrimidine Carboxylate Ester; 5-Hydroxy-6-methoxy-2-[1-methyl-1-(N-benzylureido)ethyl]pyrimidine-4-carboxylic acid methyl ester-d3; Benzylcarbamoyl Amino Pyrimidine Derivative-D3; Deuterated API Intermediate; [D3]-Labeled Pyrimidine Ester
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-2-[1-Methyl-1-[[Benzylcarbamoyl]Amino]Ethyl]-6-Methoxypyrimidine-4-Carboxylic Acid Methyl Ester-D3 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and isotopic enrichment verification, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, assay, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.