Description

Gemfibrozil-D6 is a deuterium-labeled internal standard of the lipid-regulating agent gemfibrozil, essential for precise quantitative analysis in bioanalytical research. This high-purity stable isotope-labeled compound is critical for ensuring accuracy and reliability in pharmacokinetic and metabolic studies, where it compensates for matrix effects and instrument variability. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in method development and validation for drug metabolism and bioequivalence studies.

Application

• Used as an internal standard for the accurate quantification of gemfibrozil in biological matrices (e.g., plasma, serum, urine) via LC-MS/MS and GC-MS.
• Essential for conducting high-quality pharmacokinetic (PK) and bioavailability/bioequivalence (BA/BE) studies in clinical research.
• Facilitates drug metabolism and disposition (DMPK) studies to understand the metabolic profile of gemfibrozil.
• Supports the development and validation of robust analytical methods in compliance with GLP and FDA/EMA guidelines.
• Enables precise monitoring of therapeutic drug levels in patient samples for clinical diagnostics and toxicology.
• Applied in forensic and anti-doping analysis for the definitive identification and measurement of gemfibrozil.

Basic Information

Product Name	Gemfibrozil-D6
CAS No.	1184986-45-5
Molecular Formula	C15H16D6O3
Molecular Weight	256.38 g/mol
Synonyms	5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic-3,3,4,4,5,5-d6 acid; Gemfibrozil (hexadeuterated); Gemfibrozil-d6; Lopid-d6; Deuterated Gemfibrozil; 2,2-Dimethyl-5-(2,5-xylyloxy)valeric-d6 Acid; 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic Acid-d6
EINECS	Contact for details

Quality Control

Our Gemfibrozil-D6 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, meeting the stringent requirements of analytical reference standard applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for isotopic purity (D-enrichment), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee consistency and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0% (chemical purity)
Isotopic Purity	≥98.0 atom % D
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.