Description

3-Bromo-2-Methylphenylboronic Acid is a versatile organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecular architectures through pivotal cross-coupling reactions. This high-purity intermediate is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides by constructing complex aryl-aryl bonds.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized to build molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name	3-Bromo-2-Methylphenylboronic Acid
CAS No.	1184298-27-8
Molecular Formula	C7H8BBrO2
Molecular Weight	214.86 g/mol
Synonyms	(3-Bromo-2-methylphenyl)boronic acid; 2-Methyl-3-bromophenylboronic acid; 3-Bromo-o-tolylboronic acid; Boronic acid, B-(3-bromo-2-methylphenyl)-; 3-Bromo-2-methylbenzeneboronic acid; 3-Bromo-2-tolylboronic acid; CAS 1184298-27-8
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.