Description

Glycine, N-(4-Fluorophenyl)-, 1,1-Dimethylethyl Ester is a specialized fluorinated amino acid derivative, serving as a crucial protected intermediate in advanced organic synthesis. Its value lies in providing a reactive glycine moiety with a fluorine-substituted aromatic group, enabling precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of peptide mimetics, protease inhibitors, and other bioactive molecules containing fluorophenyl glycine motifs.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators where the fluorine atom enhances bioavailability and stability.
• Chemical Biology & Proteomics: Serves as a precursor for labeled amino acids or probes used in studying enzyme mechanisms and protein interactions.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers and advanced materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis projects requiring fluorinated amino acid derivatives.

Basic Information

Product Name	Glycine, N-(4-Fluorophenyl)-, 1,1-Dimethylethyl Ester
CAS No.	1184105-23-4
Molecular Formula	C13H18FNO2
Molecular Weight	239.29 g/mol
Synonyms	tert-Butyl N-(4-fluorophenyl)glycinate; N-(4-Fluorophenyl)glycine tert-Butyl Ester; 2-[(4-Fluorophenyl)amino]acetic acid 1,1-dimethylethyl ester; 4-Fluorophenylglycine tert-butyl ester; Boc-4-F-Phe-OH (common misnomer, related protected form); (4-Fluoroanilino)acetic acid tert-butyl ester; Glycine, N-(p-fluorophenyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of Glycine, N-(4-Fluorophenyl)-, 1,1-Dimethylethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.