Description

1,3-Dibromo-2-(Difluoromethoxy)Benzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which incorporates both bromine and fluorine substituents, making it a versatile precursor for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring difluoromethoxy and bromoaryl motifs.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers and specialty polymers, such as polyarylates, where the halogenated structure can influence thermal and optical properties.
• Fluorine Chemistry Studies: An important substrate for investigating new fluorination methodologies and the behavior of difluoromethoxy groups in aromatic systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for use in client-directed custom synthesis projects requiring this specific halogenated benzene derivative.

Basic Information

Product Name	1,3-Dibromo-2-(Difluoromethoxy)Benzene
CAS No.	1182728-50-2
Molecular Formula	C7H4Br2F2O
Molecular Weight	305.91 g/mol
Synonyms	2-(Difluoromethoxy)-1,3-dibromobenzene; 1,3-Dibromo-2-(difluoromethoxy)benzene; Benzene, 1,3-dibromo-2-(difluoromethoxy)-; 2-(Difluoromethoxy)-m-dibromobenzene; m-Dibromo-o-(difluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Every batch of 1,3-Dibromo-2-(Difluoromethoxy)Benzene is produced and tested under a strict quality management system. We ensure the product meets high-purity standards suitable for research and process development applications. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles as determined by techniques including HPLC, GC, and NMR, is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.