Description

Benzeneacetic Acid, 2-Fluoro-±-(1-Methylethyl)- is a fluorinated derivative of phenylacetic acid, serving as a versatile chiral building block in advanced organic synthesis. Its value lies in the introduction of both fluorine and a chiral isopropyl moiety, which are critical for modulating the biological activity, metabolic stability, and physical properties of target molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with tailored properties for advanced materials.
• Chemical Biology Probes: Useful for creating fluorinated analogs of bioactive molecules to study metabolic pathways and receptor interactions.

Basic Information

Product Name	Benzeneacetic Acid, 2-Fluoro-±-(1-Methylethyl)-
CAS No.	1181574-74-2
Molecular Formula	C11H13FO2
Molecular Weight	196.22 g/mol
Synonyms	2-Fluoro-α-(1-methylethyl)benzeneacetic acid; (±)-2-Fluoro-α-isopropylphenylacetic acid; DL-2-Fluoro-α-isopropylphenylacetic acid; α-Isopropyl-2-fluorophenylacetic acid; 2-Fluoro-α-(propan-2-yl)benzeneacetic acid; rac-2-Fluoro-α-isopropylphenylacetic acid; (RS)-2-Fluoro-α-(1-methylethyl)benzenecetic acid
EINECS	Contact for details

Quality Control

Our production of Benzeneacetic Acid, 2-Fluoro-±-(1-Methylethyl)- adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high chemical purity. Quality is verified against comprehensive specifications including identity, assay, chiral purity, and impurity profiles. A Certificate of Analysis (COA) documenting all test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (Racemic mixture)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.