Description

(3-Fluoro-4-Methylphenyl)(Piperazin-1-Yl)Methanone Hydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and receptor-targeting drugs. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural moiety in the research and scale-up of new therapeutic agents.
• Biochemical Research: Used in life science research for studying receptor-ligand interactions and signal transduction pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value compounds.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical laboratories.

Basic Information

Product Name	(3-Fluoro-4-Methylphenyl)(Piperazin-1-Yl)Methanone Hydrochloride
CAS No.	1181457-89-5
Molecular Formula	C12H15FN2O • HCl
Molecular Weight	258.72 g/mol (Free base: 222.26 g/mol)
Synonyms	1-[(3-Fluoro-4-methylphenyl)carbonyl]piperazine hydrochloride; (3-Fluoro-4-methylphenyl)(piperazin-1-yl)methanone HCl; 3-Fluoro-4-methyl-1-(piperazine-1-carbonyl)benzene hydrochloride; 1-(3-Fluoro-4-methylbenzoyl)piperazine hydrochloride; Piperazine, 1-[(3-fluoro-4-methylphenyl)carbonyl]-, hydrochloride; CAS 1181457-89-5
EINECS	Contact for details

Quality Control

Our (3-Fluoro-4-Methylphenyl)(Piperazin-1-Yl)Methanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all specified parameters. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.