Description

2-n-Cbz-Propane-1,2-Diamine is a protected diamine derivative featuring a carboxybenzyl (Cbz) group, a crucial intermediate in modern synthetic organic and medicinal chemistry. This compound is valued for its role as a versatile building block in the synthesis of complex molecules, particularly in peptide coupling and the development of pharmaceutical active ingredients. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for constructing novel drug candidates and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in oncology and antiviral research.
• Peptide Chemistry: Serves as a protected diamine building block for the solid-phase and solution-phase synthesis of peptides and peptidomimetics.
• Ligand and Catalyst Preparation: Used in the development of chiral ligands and catalysts for asymmetric synthesis applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating specialty polymers with amine functionality.
• Academic and R&D: Essential for methodological development and exploratory synthesis in university and industrial research laboratories.

Basic Information

Product Name	2-n-Cbz-Propane-1,2-Diamine
CAS No.	1179533-31-3
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	N2-[(Benzyloxy)carbonyl]-1,2-propanediamine; 1,2-Propanediamine, N1-[(phenylmethoxy)carbonyl]-; (2-Aminopropyl)carbamic acid benzyl ester; Cbz-1,2-diaminopropane; N-Cbz-1,2-diaminopropane; Nα-Cbz-1,2-diaminopropane; Z-1,2-Diaminopropane; Benzyl N-(2-aminopropyl)carbamate
EINECS	Contact for details

Quality Control

Our 2-n-Cbz-Propane-1,2-Diamine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and our quality protocols are designed to meet the stringent requirements of GMP and ISO guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.