Description

2-Amino-5-(2-Methyl-4-Fluorophenyl)Thiazole is a high-value, fluorinated thiazole derivative serving as a critical synthetic intermediate. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in advanced pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in pharmaceutical, agrochemical, and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom and thiazole ring enhance biological activity and environmental stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and organocatalysis.
• Material Science: A potential monomer or additive in the synthesis of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe Development: Utilized in creating molecular probes for studying enzyme function and biological pathways due to its modifiable structure.

Basic Information

Product Name	2-Amino-5-(2-Methyl-4-Fluorophenyl)Thiazole
CAS No.	1179232-29-1
Molecular Formula	C10H9FN2S
Molecular Weight	208.26 g/mol
Synonyms	2-Amino-5-(2-methyl-4-fluorophenyl)-1,3-thiazole; 5-(2-Methyl-4-fluorophenyl)-1,3-thiazol-2-amine; 2-Amino-5-(2-methyl-4-fluorophenyl)thiazole; 2-Amino-5-(2-methyl-4-fluorophenyl)-thiazole; 2-Amino-5-(2-methyl-4-fluorophenyl)-δ²-thiazoline
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(2-Methyl-4-Fluorophenyl)Thiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to ensure traceability and compliance with your R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.