Description

(4-Bromo-2-Fluorophenyl)Methanesulfonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its core value lies in its reactive sulfonyl chloride and halogenated aryl structure, enabling precise molecular construction. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine and bromine substituents for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Sulfonamide Library Construction: A versatile reagent for high-throughput synthesis and medicinal chemistry campaigns aimed at discovering new sulfonamide-based drug candidates.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences sector.

Basic Information

Item	Detail
Product Name	(4-Bromo-2-Fluorophenyl)Methanesulfonyl Chloride
CAS No.	1178830-06-2
Molecular Formula	C7H5BrClFO2S
Molecular Weight	287.53 g/mol
Synonyms	4-Bromo-2-fluorobenzenemethanesulfonyl chloride; 1-Bromo-4-(chlorosulfonylmethyl)-3-fluorobenzene; (4-Bromo-2-fluorobenzyl)sulfonyl chloride; 2-Fluoro-4-bromobenzylsulfonyl chloride; α-Chlorosulfonyl-4-bromo-2-fluorotoluene; 4-Bromo-2-fluoro-α-(chlorosulfonyl)toluene; (4-Bromo-2-fluorophenyl)methylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of (4-Bromo-2-Fluorophenyl)Methanesulfonyl Chloride is manufactured under strict quality management systems. We guarantee high chemical purity and consistency, supported by comprehensive analytical testing including HPLC, NMR, and GC-MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.